Prevalence of microalbuminuria in Type-2 diabetes mellitus (DM) (negative by strip test)

Prevalence of microalbuminuria in Type-2 diabetes mellitus (DM) (negative by strip test)

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Diabetic Nephropathy and end-stage renal failure are still a major cause of mortality amongst patients with diabetes mellitus.Microalbuminuria has been shown to be a strong predictor of progressive renal disorders and a potent risk marker for cardiovascular disease.However the prevalence of microalbuminuria in DM type 2 patients in Thai people is less certain.Thus, we examined the prevalence of microalbuminuria in DM.

patients in Lampang Hospital study.Two hundred seventy patients with DM type 2 attending to outpatient medical unit were randomly selected.In a first interview, a strip test for protein was performed on a singe-spot morning urine Duvet Insert sample (no hematuria).The patient was excluded if proteinuria was present; if proteinuria was absent an microalbuminuria and creatinine were performed by automated chemistry analyzer.

Urine albumin-to-creatinine ratio was calculated.Blood sample was obtained to determine glucose and HbA1C.Prevalence of microalbuminuria (MA) was 24.8%, normal function (NF) was found in 66.

2% and overt nephropathy (ON) in 9%, Fasting Blood glucose and HbA1C were poorly controlled in all groups.Conclusion: Microalbuminuria; the presence of low but abnormal levels of albumin in the urine is the earliest sign of nephropathy and specific to diabetic nephropathy.Bull Chiang Mai Assoc Med Sci Fridge Icemaker Hose 2008; 41: 103-110.